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SMRATI BHADAURIA |
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Sr. Scientist
Toxicology Division
Central Drug Research Institute,
Lucknow-226 031 |
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| Educational Qualifications |
M.Sc.(Biochemistry), Ph.D (Biochemistry) |
| Phone |
+91-522-2772450 Ext. 4575 |
| Fax |
+91-522-2771942 |
| E-Mail |
[email protected] [email protected] |
| Date of Birth |
22.06.1978 |
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| POST
DOCTORAL RESEARCH EXPERIENCE |
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Cell Stress Biology, Roswell Park Cancer Institute Buffalo (NY) USA |
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| CURRENT
AREAS OF INTEREST |
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Role of Estrogen(s) Induced Redox Alteration in Breast Carcinogenesis |
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Role of Tumor Associated Macrophages in Breast Cancer Metastasis |
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Regulatory Toxicology |
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| RESEARCH
GROUP MEMBERS |
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Presently Working
Mr. Anurag Srivastava ( JTA)
Mr Chakrapani Tripathi (SRF)
Mr. Khemraj Baghel(SRF)
Mr. Mehraj-U-Din-Lone (JRF)
Past Member
Mr. A.R Shinde (Technician) |
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| SELECTED
PUBLICATIONS |
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Estrogen Receptor Potentiates mTORC2 Signaling in Breast Cancer Cells by Upregulating Superoxide Anions : Ranjana Kumari Kanchan , Chakrapani Tripathi , Khemraj Singh Baghel , Shailendra Kumar Dwivedi , Balawant Kumar, Sabyasachi Sanyal , Sharad Sharma , Kalyan Mitra ,Vivek Garg, Kavita Singh , Sarvat Sultana , Raj Kamal Tripathi, Srikanta Kumar Rath, Smrati BhadauriaFree Radical Biology and Medicine 53 (10): 1929-1941. ( 2012) |
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Glycine soya diet synergistically enhances the suppressive effect of tamoxifen and inhibits tamoxifen-promoted hepatocarcinogenesis in 7,12-dimethylbenz [α] anthracene-induced rat mammary tumor model. Rajeev Mishra, Smrati Bhadauria, P.K. Murthy, P.S.R. Murthy Food and Chemical Toxicology 49 (2): 434-440. (2011) |
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Therapeutic effect of centchroman alone and in combination with glycine soya on 7, 12-dimethylbenz [α] anthracene –induced breast tumor in rat.
Rajeev Mishra, Ashutosh Tiwari, Smrati Bhadauria, Jyoti Mishra, P.K Murthy and P.S.R Murthy. Food and Chemical Toxicology 48(6): 1587-91(2010) |
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Monoisoamyl 2, 3-Dimercaptosicinic Acid (MiADMSA) Demonstrated Higher Efficacy by Oral Route in Reversing Arsenic Toxicity: A Pharmacokinetic Approach. Swaran.J.S Flora, Smrati Bhadauria, Vidhu Pachauri and Abhishek Yadav Basic and Clinical Pharmacology and Toxicology. 110 (5): 449–459. (2011) |
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Isoniazid-induced apoptosis in HepG2 cells: Generation of oxidative stress and Bcl-2 down regulation.Smrati Bhadauria, Rajeev Mishra, Ranjana Kanchan, Chakrapani Tripathi, Anurag Srivastava, Asutosh Tiwari and Sharad Sharma. Toxicology Mechanisms and Methods 20(5):242-51 (2010). |
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Evaluation of Adverse Cardiac Effects Induced by Arsenic Trioxide, a Potent Anti-APL Drug K.G. Raghu, Govind KumarYadav, Richa Singh, A Prataphan, Sharad Sharma and Smrati Bhadauria Journal of Environmental Pathology , Toxicology and Oncology 28(3), 241-252 (2009) |
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Isoniazid Induces Oxidative Stress, Mitochondrial Dysfunction and Apoptosis in Hep-G2 Cells. Smrati Bhadauria, Gyanendra Singh, , Neeraj Sinha, Sudhir Srivastava Cellular and Molecular Biology 53(1), 102-114 (2007) |
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Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: A review S.J.S Flora, Smrati Bhadauria, G.M. Kannan and Nutan Singh Journal of Environmental Biology 28(2), 333-347(2007) |
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Response of arsenic induced blood and brain oxidative stress to some thiol chelators in male rats. Flora SJ, Bhadauria S, Pant SC, Dhaked RK. Life sciences 77, 2324-2337, (2005) |
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Response of arsenic induced blood and brain oxidative stress to some thiol chelators in male rats. Flora SJ, Bhadauria S, Pant SC, Dhaked RK.
Life sciences 77, 2324-2337, (2005) |
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Combined Administration Of Thiol Chelators On Arsenic Mobilization and Tissue Oxidative Stress In Chronic Arsenic Exposed Male Rats.
Bhadauria. S. and S.J.S.Flora Journal of Tissue Research 4, 95-100 (2004) |
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Lead Induced Oxidative Stress and Its Response to Combined Administration of Taurine and Dimercaptosuccinic Acid in Male Rats Manisha Pande, Smrati Bhadauria, G.M.Kannan and S.J.S.Flora Human and Experimental Toxicology, 23, 157-166(2004) |
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(10)Arsenic Induced Inhibited d-Aminolevulinate Dehydratase Activity in Rat Blood and Its Response to Meso 2,3-Dimercaptosuccinic Acid and Monoisoamyl DMSA.Smrati Bhadauria and S.J.S.Flora Biomedical and Environmental Sciences 17,305-313(2003) |
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